Mutated antithrombins, a process for preparing the same and their use as drugs

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United States of America Patent

PATENT NO 8822654
APP PUB NO 20120088715A1
SERIAL NO

13144995

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Abstract

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The present invention relates to the use of a composition including of at least a mutated antithrombin

    having an anticoagulant activity substantially reduced with respect to the anticoagulant activity of the non mutated antithrombin, orhaving no anticoagulant activity,for the preparation of a drug intended for the prevention or the treatment of pathologies associated with cellular injury, such as infection, inflammation or hypoxic injury.

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Patent Owner(s)

Patent OwnerAddress
ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS3 AVENUE VICTORIA PARIS FR-75100
UNIVERSITE PARIS-SUD XI15 RUE GEORGES CLEMENCEAU ORSAY CEDEX F-91405
UNIVERSITE PARIS DESCARTES12 RUE DE L'ECOLE DE MEDECINE PARIS CEDEX 06 F-75270

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bianchini, Elsa Villebon sur Yvette, FR 4 29
Borgel, Delphine Paris, FR 2 0
Diehl, Jean-Luc René Clamart, FR 1 0
Ferger, Véronique Sceaux, FR 1 0
Lerolle, Nicolas Angers, FR 1 0

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