Mimetic peptides and the use thereof in the form of 20S, 26S and immunoproteasome inhibitors

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United States of America Patent

PATENT NO 8835392
APP PUB NO 20090012007A1
SERIAL NO

11817628

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Abstract

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The present invention relates to peptide-mimetic compounds, the synthesis and use thereof fort he inhibition of proteasomes and the induction of apoptosis in tumor cells. The present invention furthermore relates to pharmaceutical compositions comprising the compounds and the use of the compounds for a treatment of diseases, in particular cancer and neurodegenerative diseases.

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Patent Owner(s)

  • CHARITE-UNIVERSITAETSMEDIZIN BERLIN;TECHNISCHE UNIVERSITAT DARMSTADT;TECHNISCHE UNIVERSITÄT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Braun, Hannes Hofheim, DE 3 4
Kloetzel, Peter-Michael Berlin, DE 1 1
Kuckelkorn, Ulrike Berlin, DE 1 1
Schmidt, Boris Darmstadt, DE 14 63
Umbreen, Sumaira Darmstadt, DE 2 3

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