Ultra-sensitive detection of molecules on single molecule arrays
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United States of America Patent
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Sep 30, 2014
Grant Date -
Aug 28, 2014
app pub date -
Jun 19, 2012
filing date -
Sep 23, 2008
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Abstract
The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample. Methods of the present invention may comprise immobilizing a plurality of analyte molecules or particles to form a plurality of complexes, releasing at least a portion of some of the plurality of complexes, determining at least a portion of the plurality of complexes released, and determining a measure of the concentration of the analyte molecules or particles in a fluid sample.
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