Methods and compositions for controlling assembly of viral proteins

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8865188
SERIAL NO

13609234

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Provided herein are methods and compositions for controlling assembly of modified viral core proteins, for example, into a viral capsid or a nanocage. In some embodiments, the disclosed modified viral core proteins comprise at least one mutation or modification that can substantially prevent assembly of the viral core proteins until assembly is desired. In some embodiments, assembly of the viral core proteins may be triggered, for example, by contacting the viral core proteins with a reducing agent and/or by reducing the concentration of a denaturant. The viral core proteins may self-assemble to form a viral capsid or nanocage.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
BIOMED REALTY L P17190 BERNARDO CENTER DRIVE SAN DIEGO CA 92128

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
de, los Rios Miguel Del Mar, US 19 112
de, los Rios Stephanie Del Mar, US 8 38
Oh, Kenneth J Pleasant Hill, US 12 149
Ostrowski, Jacek Encinitas, US 18 172
Zipkin, Ilan Belmont, US 2 5

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
11.5 Year Payment $7400.00 $3700.00 $1850.00 Apr 21, 2026
Fee Large entity fee small entity fee micro entity fee
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00