Orodispersible tablets of bitter active principles

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United States of America Patent

PATENT NO 8865219
APP PUB NO 20080248111A1
SERIAL NO

12088205

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Abstract

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The invention concerns coated granules including (A) at least one amine-containing pharmacological active principle, preferably as an acid addition salt, the pharmacological active principle being complexed by low cation-exchange resin containing carboxylic acid groups (COO″), and (B) at least 15 wt. %, based on the total weight of the active principle/low cation-exchange resin complex, of at least one hydrophilic adsorbent, the mixture of the components (A) and (B) being coated with a gastrosoluble polymer. The invention also concerns a method for preparing such granules, as well as orodispesible tablets containing such granules.

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Patent Owner(s)

Patent OwnerAddress
ETHYPHARM92210 SAINT-CLOUD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chaudhari, Mahendra B Maharashtra, IN 3 2
Gendrot, Edouard Garnay, FR 10 410

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