Method, computer program, and apparatus for detecting pipetting errors
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United States of America Patent
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Oct 28, 2014
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app pub date -
Sep 27, 2010
filing date -
Sep 25, 2009
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Abstract
Pipetting errors are detected by: (a) during pipetting, measuring the pressure in the tip of a pipetting device and determining an earlier rate of change of the pressure in the tip; (b) based on the earlier rate of pressure change and a previous pressure value pi, determining an expectation range for the pressure pi+1 at a further moment in time and/or an expectation range for the rate of pressure change δi+1 based on the pressure at the further moment in time ti+1; (c) at the further moment in time ti+1 measuring the pressure pi+1 in the tip; and (d) determining the occurrence of a pipetting error by comparing the measured pressure pi+1 at the further moment ti+1 in time and/or a rate of pressure change δi+1 calculated on the basis of the pressure pi+1 at the further moment ti+1 in time.
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