Vortex structure for high throughput continuous flow separation

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United States of America Patent

PATENT NO 8875903
SERIAL NO

11725358

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Abstract

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A system to facilitate separation and concentration of particles based on centrifugal force on suspended particles, including biological matter, which are made to flow in a vortex structure is provided. The centrifugal force urges larger particles to collect along outer portions of the vortex flow. Conversely, within a vortex structure, a radial hydrodynamic pressure drop is also amplified to urge smaller particles toward inner portions of the vortex flow. This force created by the pressure can reach magnitudes that encourage a sharp cut-off and improved resolution discrimination between particle sizes. Thus, separated streams of particles can be collected with both increased concentration and purification.

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Patent Owner(s)

Patent OwnerAddress
PALO ALTO RESEARCH CENTER INCORPORATED3333 COYOTE HILL ROAD PALO ALTO CA 94304

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lean, Meng H Santa Clara, US 93 1731
Seo, Jeonggi Albany, US 23 520

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