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United States of America Patent

PATENT NO 8883226
SERIAL NO

13985533

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Abstract

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A pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma comprising the extract of Decaspermum fruticosum as an active ingredient. The extract of Decaspermum fruticosum of the present invention inhibited the increase of eosinophils in bronchoalveolar lavage fluid of the ovalbumin induced asthma animal model, had the activity of inhibiting the secretions of immunoglobulin and chemokine (Eotaxin) in bronchoalveolar lavage fluid and blood, and inhibited the secretions of NO and TNF-α in macrophages. Therefore, the extract of Decaspermum fruticosum of the present invention can be effectively used as an active ingredient of a pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma, and of a health functional food for the prevention and improvement of inflammatory disease or asthma.

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Patent Owner(s)

  • KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahn, Kyung Seop Daejeon, KR 40 22
Jin, Hang Yunnan, CN 171 2884
Joung, Hyouk Daejeon, KR 5 6
Kwon, Ok-Kyoung Daejeon, KR 20 1
Lee, Hyeong Kyu Daejeon, KR 20 10
Lee, Joongku Daejeon, KR 4 3
Lee, Kyoung-youl Daejeon, KR 2 0
Lee, Mee-Young Daejeon, KR 11 45
Lee, Sang Woo Daejeon, KR 138 937
Li, Wan Yi Yunnan, CN 6 0
Oh, Sei Ryang Daejeon, KR 26 23
Son, Hwa-Young Daejeon, KR 2 0

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