C—glycolipids with enhanced Th-1 profile

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United States of America Patent

PATENT NO 8883745
SERIAL NO

12302011

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Abstract

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The invention is directed to novel synthetic C-glycolipids that selectively induce a ThI-type immune response characterized by enhanced IL-12 secretion and increased activation of dendritic cells. The compounds of the invention are thereby useful in treating infections, cancers, cell proliferative disorders, and autoimmune diseases, both directly and as adjuvants.

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Patent Owner(s)

Patent OwnerAddress
NEW YORK UNIVERSITY70 WASHINGTON SQUARE SOUTH NEW YORK NY 10012-1091
THE AARON DIAMOND AIDS RESEARCH CENTER FOR THE CITY OF NEW YORK INC455 FIRST AVENUE NEW YORK NY 10016

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Guangwu Flushing, US 18 74
Franck, Richard W Riverside, US 2 1
Tsuji, Moriya New York, US 19 410
Yang, Guangli Forest Hills, US 31 353

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