Fluorescent membrane intercalating probes and methods for their use
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United States of America Patent
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Nov 25, 2014
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app pub date -
Nov 17, 2006
filing date -
Nov 18, 2005
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Abstract
The invention relates to a family of dyes which fluoresce in the UV-VIS, far red and near infrared wavelengths of the spectrum and possess asymmetric lipophilic alkyl chains. The dyes of the invention are soluble in commercially available membrane staining dyes, are useful as probes for rapidly staining lipophilic structures such as membranes in cells or isolated from cells, and are well-retained therein. Methods of utilizing the dyes to detect stained cells both in vivo and in vitro are also disclosed.
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