Method of cell culture and method of treatment comprising a vEPO protein variant

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United States of America Patent

PATENT NO 8895303
SERIAL NO

12514773

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Abstract

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In one aspect the present invention is concerned with a method of cell culture, comprising the steps of (i) obtaining a stem or progenitor cell sample, (ii) culturing the stem or progenitor cell sample in media and under closed conditions appropriate to cause proliferation or differentiation of the stem or progenitor cells, wherein the media comprises a vEPO protein variant, (iii) purifying the stem or progenitor cells ex vivo. The invention relates to a method of increasing the number and survival of stem and progenitor cells in vitro and in vivo using a vEPO protein variant. The invention also relates to improved differentiation of stem and progenitor cells in vitro and in vivo using a vEPO protein variant.

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Patent Owner(s)

  • CHARITE-UNIVERSITATSMEDIZIN BERLIN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bonnas, Christel Berlin, DE 3 13
Meisel, Andreas Berlin, DE 36 1781
Priller, Josef Berlin, DE 5 13

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