Antibody that binds domain 2 of ICAM-1 and methods of treatment

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United States of America Patent

PATENT NO 8900586
SERIAL NO

14128815

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Abstract

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The present invention relates to an antibody binding to the domain 2 of human intercellular adhesion molecules-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and induce antigen-specific T cell tolerance, thereby be effective in the prevention and/or treatment of T cell-mediated immune disorders such as transplantation rejection, graft-versus-host disease, and autoimmune disease. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.

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Patent Owner(s)

Patent OwnerAddress
KUMHO HT INC717 YONGA-RO GWANGSAN-GU GWANGJU 62214

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jung, Kyeong Cheon Seoul, KR 3 8
Park, Seong Hoe Seoul, KR 6 17

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