Method of regulating proliferation and differentiation of keratinocyes

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United States of America Patent

PATENT NO 8912142
APP PUB NO 20110207665A1
SERIAL NO

13127058

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Abstract

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Provided are methods of regulating keratinocytes proliferation and differentiation by subjecting keratinocytes to an agent capable of modulating activity or expression of IGFBP7, thereby regulating keratinocytes proliferation and differentiation. Also provided are methods of treating pathologies characterized by hyperproliferative keratinocytes by administering IGFBP7 polypeptide or a polynucleotide encoding IGFBP7 polypeptide to a subject.

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Patent Owner(s)

Patent OwnerAddress
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDHAIFA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Nousbeck, Janna Givataim, IL 1 5
Sprecher, Eli Tel-Aviv, IL 7 9

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