Preparation of nucleosides ribofuranosyl pyrimidines

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United States of America Patent

PATENT NO 8912321
SERIAL NO

12444608

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Abstract

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The present process provides an improved method for the preparation of 4-amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-hydroxymethyl-3-methyl-tetrahydrofuran-2-yl)-1H-pyrimidin-2-one of the formula (IV) which is a potent inhibitor of Hepatitis C Virus (HCV) NS5B polymerase.

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Patent Owner(s)

Patent OwnerAddress
GILEAD PHARMASSET LLC333 LAKESIDE DRIVE FOSTER CITY CA 94404

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Axt, Steven D Menlo Park, US 7 91
Chun, Byoung-Kwon Robbinsville, US 45 1248
Jin, Quingwu San Jose, US 1 23
Rachakonda, Suguna Robbinsville, US 22 863
Ross, Bruce Plainsboro, US 28 811
Sarma, Keshab Sunnyvale, US 28 765
Vitale, Justin San Mateo, US 7 85
Zhu, Jiang Cupertino, US 283 2679

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