Optimized non-canonical zinc finger proteins

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United States of America Patent

PATENT NO 8921112
SERIAL NO

12286668

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Abstract

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Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are also described.

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Patent Owner(s)

  • DOW AGROSCIENCES LLC;SANGAMO BIOSCIENCES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arnold, Nicole L Carmel, US 10 212
Baker, Lisa W Carmel, US 4 93
Blue, Ryan C Fishers, US 12 172
Cai, Qihua C Westfield, US 5 91
Garrison, Robbi J Fillmore, US 10 110
Miller, Jeffrey Pleasanton, US 95 1826
Mitchell, Jon C Zionsville, US 11 118
Petolino, Joseph F Zionsville, US 35 626
Shukla, Vipula K Indianapolis, US 4 155
Urnov, Fyodor Port Richmond, US 106 4635
Worden, Sarah E Fillmore, US 45 183

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