Methods and compositions for targeted integration

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United States of America Patent

PATENT NO 8936936
SERIAL NO

12288847

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Abstract

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Disclosed herein are methods and compositions for targeted integration of one or more copies of a sequence of interest using zinc finger nucleases (ZFNs) comprising a zinc finger protein and a cleavage domain or cleavage half-domain and integrase defective lentiviral donor constructs.

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Patent Owner(s)

  • OSPEDALE SAN RAFFAELE S.R.L.;SANGAMO BIOSCIENCES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Holmes, Michael C Oakland, US 87 3590
Lombardo, Angelo Leone Sangano, IT 7 16
Naldini, Luigi Pioltello, IT 49 1043
Yao, Shuyuan San Diego, US 2 106

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