Compositions and uses thereof for the treatment of wounds

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United States of America Patent

PATENT NO 8946381
APP PUB NO 20100166835A1
SERIAL NO

12441691

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides a topical composition comprising (i) an amount of an AP-1 signaling inhibitor sufficient to reduce, delay or prevent apoptosis and/or necrosis induced by dermal wounding and/or to induce and/or enhance proliferation of a cell; and (ii) a suitable carrier or excipient e.g., a topical carrier or excipient or other carrier or excipient for dermal application. For example, the AP-1 signaling inhibitor is a peptide analog comprising the sequence set forth in SEQ ID NO: 104. The present invention also provides a method of treating a dermal wound comprising topically administering said topical composition to a subject suffering from a dermal wound.

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Patent Owner(s)

  • PHYLOGICA LIMITED;THE MCCOMB FOUNDATION, INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fear, Mark Mundaring, AU 6 33
Hopkins, Richard North Perth, AU 36 137
Milech, Nadia Daglish, AU 5 10
Watt, Paul Mount Claremont, AU 10 67

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