Lipidated imidazoquinoline derivatives

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United States of America Patent

PATENT NO 8946421
SERIAL NO

14135900

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Abstract

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The compounds of the subject invention are adjuvant molecules that comprise an imidazoquinoline molecule covalently linked to a phospho- or phosphonolipid group. The compounds of the invention have been shown to be inducers of interferon-a, IL-12 and other immunostimulatory cytokines and possess an improved activity profile in comparison to known cytokine inducers when used as adjuvants for vaccine antigens.

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Patent Owner(s)

  • SMITHKLINE BEECHAM BIOLOGICALS S.A.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Johnson, David A Hamilton, US 250 4060

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