Compositions and methods for treatment of cervical dysplasia

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United States of America Patent

PATENT NO 8956621
SERIAL NO

13314583

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Abstract

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The present invention provides methods of treating, protecting against, and inducing an immune response against cervical dysplasia and cancer, comprising the step of administering to a subject a recombinant Listeria strain, comprising a fusion peptide that comprises an LLO fragment and an E7 and/or E6 antigen. The present invention also provides methods for inducing an anti-E7 CTL response in a human subject and treating HPV-mediated diseases, disorders, and symptoms, comprising administration of the recombinant Listeria strain.

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Patent Owner(s)

Patent OwnerAddress
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA3600 CIVIC CENTER BOULEVARD 9TH FLOOR PHILADELPHIA MA 19104

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Paterson, Yvonne Philadelphia, US 59 1982
Rothman, John Lebanon, US 38 447

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