Secondary 8-hydroxyquinoline-7-carboxamide derivatives for use as antifungal agents

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United States of America Patent

PATENT NO 8969380
APP PUB NO 20120329797A1
SERIAL NO

13519439

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Abstract

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The present invention provides secondary 8-hydroxyquinoline-7-carboxamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful as antifungal agents. Specifically, these compounds were tested against Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger and Scopulariopsis Brevicaulis. These compounds are active against Candida species such as Candida Albicans and Candida Glabrata.

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Patent Owner(s)

  • POLICHEM SA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Del, Sordo Simone Treviglio, IT 7 8
Gagliardi, Stefania Vimercate, IT 44 143
Legora, Michela Appiano Gentile, IT 8 12
Mailland, Federico Lugano, CH 37 179

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