Triterpenoid derivatives useful as antiproliferative agents
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United States of America Patent
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Mar 3, 2015
Grant Date -
May 24, 2012
app pub date -
May 20, 2010
filing date -
May 20, 2009
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Abstract
Formula (I) and (II). The present invention relates to the use of a new lupane derivative of general formula (I) or (II), or a pharmaceutically acceptable salt, crystal form, complex, hydrate, or hydrolysable ester thereof, for preventing and/or inhibiting tumor growth and for treating cancer and other proliferative diseases, more particularly for treating leukemia, liver, cervical, colon and prostate cancer. The present invention also relates to the synthesis of these compounds and to pharmaceutical compositions which contain them.
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