Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
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United States of America Patent
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Mar 31, 2015
Grant Date -
May 5, 2011
app pub date -
Nov 1, 2010
filing date -
Oct 30, 2009
priority date (Note) -
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Abstract
Methods and devices for the treatment of chronic pain by modulation of the cholinergic anti-inflammatory pathway. In particular, the methods and systems described herein may be used to enhance chronic pain therapies such as spinal cord stimulation (SCS). Thus, the present invention describes devices and methods for modulation of the cytokine pathway by stimulation of the neuronal cholinergic anti-inflammatory pathway (NCAP) to enhance the treatment of chronic pain by SCS. The use of NCAP in conjunction with SCS may potentiate the effects of SCS and/or prevent the desensitization of the patient to SCS.
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