Increase of myeloid microvesicles in the cerebrospinal fluid as biomarker of microglia/macrophage activation in neurological disorders

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United States of America Patent

PATENT NO 8999655
APP PUB NO 20130040318A1
SERIAL NO

13581646

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Abstract

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The present invention relates to a method for the diagnostic and/or prognostic of a neurological disease characterized by an inflammation process in a subject comprising measuring the amount of myeloid derived microvesicles in a cerebrospinal fluid sample obtained from the subject. The invention further relates to a method for predicting and/or monitoring the efficacy of a treatment for a neurological pathology or for monitoring a neurological disease progression.

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Patent Owner(s)

Patent OwnerAddress
OSPEDALE SAN RAFFAELE S R L20132 MILANO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Furlan, Roberto Milan, IT 5 43
Matteoli, Michela Milan, IT 1 1
Verderio, Claudia Rome, IT 2 4

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