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United States of America Patent

PATENT NO 9023656
APP PUB NO 20100178710A1
SERIAL NO

11996910

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Abstract

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A mass label for labelling and detecting a biological molecule by mass spectroscopy, which label comprises the following structure: X-L-M wherein X is a mass marker moiety comprising the following group: formula (I), wherein the cyclic unit is aromatic or aliphatic and comprises from 0-3 double bonds independently between any two adjacent atoms; each Z is independently N, N(R1), C(R1), CO, CO(R1), C(R1)2, O or S; X is N, C or C(R1); each R1 is independently H, a substituted or unsubstituted straight or branched C1-C6 alkyl group, a substituted or unsubstituted aliphatic cyclic group, a substituted or unsubstituted aromatic group or a substituted or unsubstituted heterocyclic group; and y is an integer from 0-10, L is a cleavable linker comprising an amide bond and M is a mass normalization moiety.

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Patent Owner(s)

Patent OwnerAddress
ELECTROPHORETICS LIMITEDLONDON WC1H 9BB

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Becker, Wolfgang Eppstein, DE 78 1074
Hamon, Christian Kriftel, DE 26 493
Kienle, Stefan Frankfurt am Main, DE 13 84
Kuhn, Karsten Hofheim am Taunus, DE 23 127
Schaefer, Juergen Lauterbach, DE 35 138
Schwarz, Josef Frankfurt am Main, DE 18 154

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