Protofibril selective antibodies and the use thereof

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United States of America Patent

PATENT NO 9034334
APP PUB NO 20120076726A1
SERIAL NO

13219012

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Abstract

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The invention relates to an isolated antibody, or fragment thereof, having high affinity for human Aβ protofibrils. The invention further relates to compositions that include the antibody, or a fragment thereof, and a pharmaceutically acceptable buffer. The invention further relates to a method of preventing or treating Alzheimer's disease, which includes the step of administering to a patient having or suspected of having Alzheimer's disease such an antibody, or fragment thereof or a composition that includes the antibody or a fragment thereof.

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Patent Owner(s)

  • BIOARCTIC NEUROSCIENCE AB

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ekholm, Pettersson Frida Uppsala, SE 2 66
Englund, Hillevi Uppsala, SE 2 66
Gellerfors, Pär Lidingö, SE 12 153
Lannfelt, Lars Stockholm, SE 25 416
Sehlin, Dag Uppsala, SE 3 68

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