Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis
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United States of America Patent
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May 19, 2015
Grant Date -
Aug 28, 2014
app pub date -
Mar 31, 2014
filing date -
Jun 26, 2009
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Abstract
The present invention relates to new salts of 6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol(rotigotine), their use as a medicament, for example for the treatment of CNS disorders like Parkinson Disease, RLS, fibromyalgia and/or depression, in particular through electromotive administration. The present invention relates to pharmaceutical formulations suitable for iontophoresis that provide enhanced iontophoretic delivery of rotigotine to at least one target tissue. The formulations are further characterized by good to excellent solubility of the salts in aqueous solutions.
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