Synthetic analogues of neural regeneration peptides

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United States of America Patent

PATENT NO 9040485
APP PUB NO 20130231289A1
SERIAL NO

13651884

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Embodiments of this invention include synthetic compounds (NRP analogues) of peptides termed neural regeneration peptides (NRPs). NRP analogues are made by substituting amino acids in the native peptide sequence, modifying amino acids chemically, by replacing amino acids with synthetic moieties, by stabilizaing β-turns, acetylation of terminal glycine residues or by cyclization. NRP analogues can be used to treat a variety of conditions involving degeneration of neural cells, and includes treating disorders of the nervous system, including peripheral neuropathy, multiple sclerosis, diabetic peripheral neuropathy, neurotoxin-induced neurodegeneration, and amyotrophic lateral sclerosis.

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Patent Owner(s)

Patent OwnerAddress
CURONZ HOLDINGS COMPANY LIMITEDAUCKLAND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brimble, Margaret Ann Auckland, NZ 2 1
Harris, Paul William Richard Waitakere, NZ 8 16
Sieg, Frank Auckland, NZ 15 1315

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