Filament based on hyaluronic acid in the form of free acid and method for obtaining it

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United States of America Patent

PATENT NO 9044410
APP PUB NO 20140242146A1
SERIAL NO

14269315

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Abstract

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The present invention relates to a method for preparing by wet spinning a continuous filament based on hyaluronic acid in free acid form, notably soluble in water. The preparation method according to the invention comprises the following steps: a) preparing a spinnable aqueous solution of hyaluronic acid or of a hyaluronic acid salt, preferably a sodium hyaluronate solution; b) extruding said solution to an extrusion die; c) forming the filament by passing the extruded solution into a bath of acetic acid, concentrated to more than 80%, drawing and drying. The invention also relates to a filament based on hyaluronic acid in free acid form, said filament having swelling properties in water and physiological liquids and moreover being solubilizable in water under certain conditions.

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Patent Owner(s)

  • CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITE CLAUDE BERNARD LYON I

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
David, Laurent Lyons, FR 41 247
Domard, Alain Lyons, FR 11 55
Dupasquier, Florence Paray le Monia, FR 4 24

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