Concentrated aqueous azalide formulations

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United States of America Patent

PATENT NO 9044508
APP PUB NO 20140274924A1
SERIAL NO

13843267

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Abstract

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Provided is concentrated aqueous azithromycin formulation from about from about 2%-20%, and a method of making a concentrated aqueous azithromycin formulation which includes preparing and sterilizing a first solution comprising a strong base to form a sterilized solution, dissolving the azithromycin in an aqueous solution comprising an acid consisting essentially of a strong acid, and adding the aqueous solution comprising the strong acid to the sterilized solution comprising the strong base. The strong acid has a pKa less than about −1.74 and the method is carried out without addition or use of a weak acid.

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Patent Owner(s)

Patent OwnerAddress
SUN PHARMACEUTICAL INDUSTRIES INC2 INDEPENDENCE WAY PRINCETON NJ 08540

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bowman, Lyle M Pleasanton, US 46 1491
Hou, Sui Yen Eddie Foster City, US 2 40
Nguyen, Tang Alameda, US 2 10

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