Hyaluronic acid decomposition-promoting factor and inhibitor thereof
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United States of America Patent
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Jun 16, 2015
Grant Date -
Apr 18, 2013
app pub date -
Jun 3, 2011
filing date -
Jun 4, 2010
priority date (Note) -
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status (Latency Note)
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Abstract
The present invention is directed to KIAA1199, which is a novel factor involved in decomposition of hyaluronic acid, and to use thereof. More specifically, the invention is directed to a hyaluronic acid decomposition-promoting agent containing the KIAA1199 gene and a protein encoded by the gene; to a hyaluronic acid decomposition-inhibiting agent characterized by inhibiting the activity or expression thereof (including an siRNA or a monoclonal antibody); and to a method for screening a novel hyaluronic acid decomposition-controlling agent, in which the method contains employing the expression of KIAA1199 as an index.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C12Q:MEASURING OR TESTING PROCESSES INVOLVING ENZYMES O....
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- G01N:INVESTIGATING OR ANALYSING MATERIALS BY DETERMININ....
- A61Q:USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
- C07K:PEPTIDES
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