Direct conversion of cells to cells of other lineages

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United States of America Patent

PATENT NO 9057053
SERIAL NO

13522002

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Abstract

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Methods, compositions and kits for producing functional neurons, astroctyes, oligodendrocytes and progenitor cells thereof are provided. These methods, compositions and kits find use in producing neurons, astrocytes, oligodendrocytes, and progenitor cells thereof for transplantation, for experimental evaluation, as a source of lineage- and cell-specific products, and the like, for example for use in treating human disorders of the CNS. Also provided are methods, compositions and kits for screening candidate agents for activity in converting cells into neuronal cells, astrocytes, oligodendrocytes, and progenitor cells thereof.

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Patent Owner(s)

  • THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ostermeier, Austin West Plains, US 4 37
Pang, Zhiping Stanford, US 5 37
Sudhof, Thomas C Stanford, US 18 124
Vierbuchen, Thomas Stanford, US 4 37
Wernig, Marius Stanford, US 14 176

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