Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells

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United States of America Patent

PATENT NO 9066982
SERIAL NO

14207304

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Abstract

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Intact, bacterially-derived minicells can safely introduce therapeutically effective amount of plasmid-free functional nucleic acid to target mammalian cells. To this end, functional nucleic acid can be packaged into intact minicells directly, without resort to expression constructs, the expression machinery of the host cell, harsh chemicals or electroporation.

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Patent Owner(s)

  • ENGENEIC MOLECULAR DELIVERY PTY. LTD.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brahmbhatt, Himanshu Sydney, AU 44 562
Hulf, Toby Castle Cary, GB 7 77
MacDiarmid, Jennifer Sydney, AU 44 562

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