Apparatus and method for optimized stimulation of a neurological target
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United States of America Patent
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Jul 7, 2015
Grant Date -
Oct 16, 2014
app pub date -
Jun 26, 2014
filing date -
Jul 30, 2008
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Abstract
A preferred frequency is identified, being usable to stimulate a neurological target within a mammalian body using at least one microelectrode positioned at or near the target. To establish efficient and effective stimulation, an impedance analyzer is provided for measuring electrical impedance values indicative of a microelectrode-tissue interface across a range of different frequencies. A preferred one of the measured electrical impedance values is identified as being closest to a pure resistance. The neurological target can then be stimulated at or near the frequency associated with the preferred impedance value (peak resistance frequency), thereby promoting desirable traits, such as optimum charge transfer, minimum signal distortion, increased stimulation efficiency, and prevention of microelectrode corrosion. The peak resistance frequency can be used to determine an preferred pulse shape. A target can be identified by microelectrode measurements of neuronal activity and/or impedance magnitude at peak resistance frequency.
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- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
- ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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- [Patents Count]
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Mercanzini, Andre | Renens, CH | 21 | 386 |
Renaud, Philippe | Preverenges, CH | 96 | 1522 |
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