ND2 peptides and methods of treating neurological disease

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United States of America Patent

PATENT NO 9073976
APP PUB NO 20140274906A1
SERIAL NO

13842848

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Abstract

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The invention is based in part on identifying a core region of ND2 responsible for interacting with Src to within residues 289-321 of ND2 and more particularly residues 307-321 or 310-321 of ND2. Peptides including, overlapping or from within this region can be used to inhibit ND2 interaction with Src Inhibition of this interaction is useful for treatment or prophylaxis of neurological diseases and disorders, pain and cancer.

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Patent Owner(s)

Patent OwnerAddress
NONO INCTORONTO ON M8X 1R5

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Garman, Jonathan David Thornhill, CA 49 621
Li, Rongwen Toronto, CA 1 1
Tymianski, Michael Toronto, CA 45 617

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