Low acidic species compositions and methods for producing and using the same

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United States of America Patent

PATENT NO 9085618
SERIAL NO

14077871

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Abstract

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The instant invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such low AR compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFα is detrimxental, are also provided.

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Patent Owner(s)

  • ABBVIE INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chumsae, Christopher North Andover, US 17 449
Dong, Diane D Shrewsbury, US 13 416
Gifford, Kathreen A Marlborough, US 11 362
Herigstad, Matthew Omon Charlestown, US 15 502
Kaymakcalan, Zehra Westborough, US 52 4396
Lim, Wen Chung Worchester, US 11 320
Ramasubramanyan, Natarajan Westborough, US 22 611
Subramanian, Kartik Northborough, US 47 656
Yang, Hong Worchester, US 313 2608
Yang, Lihua Westborough, US 21 353
Zeng, Xiaobei Carolina, US 27 733

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