Methods and compositions involving protective staphylococcal antigens

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United States of America Patent

PATENT NO 9095540
APP PUB NO 20130230550A1
SERIAL NO

13821943

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Abstract

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The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant. In some embodiments, the methods and compositions involve SdrD, ClfA, and/or FnbpB polypeptides.

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Patent Owner(s)

  • THE UNIVERSITY OF CHICAGO

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheng, Alice G Boston, US 10 97
Kim, Hwan Keun Naperville, US 20 304
Kim, Hye-Young Rancho Cucamonga, US 25 362
Missiakas, Dominique M Chicago, US 20 324
Schneewind, Olaf Chicago, US 46 661

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