Method for producing second-generation library

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United States of America Patent

PATENT NO 9096951
APP PUB NO 20120028812A1
SERIAL NO

13179283

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Abstract

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The present invention relates to a method for generating a second-generation library. In a first step, a library of encoded molecules associated with an identifier nucleic acid comprising codons identifying chemical entities that have participated in the formation of the encoded molecule is provided. In a second step, the library is partitioned and encoded molecules having a certain property are selected. Codons of identifiers of selected encoded molecules are subsequently identified, and a second-generation library is prepared using at least some of the chemical entities coded for by the identified codons. The new focussed library may be used for another partition step to select encoded molecules with a certain property.

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  • NUEVOLUTION A/S

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Freskgard, Per-Ola Norrkorping, SE 43 666
Gouliaev, Alex Haahr Veksoe Sjaelland, DK 43 529
Olsen, Eva Kampmann Herlev, DK 16 314
Thisted, Thomas Frederikssund, DK 58 566

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