Methods and compositions related to clot binding compounds

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United States of America Patent

PATENT NO 9101671
APP PUB NO 20080305101A1
SERIAL NO

11967509

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Abstract

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Disclosed are compositions and methods related to clot binding compounds. For example, disclosed are conjugates comprising a surface molecule and a plurality of clot binding compounds. The clot binding compounds can selectively bind to clotted plasma protein. The conjugate can, for example, cause clotting and amplify the accumulation of the conjugate in tumors. In one example, the conjugate can comprise a sufficient number and composition of clot binding compounds such that the conjugate causes clotting and amplifies the accumulation of the conjugate in tumors. The disclosed targeting is useful for treatment of cancer and other diseases and disorders.

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Patent Owner(s)

  • SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ruoslahti, Erkki LaJolla, US 116 2306
Simberg, Dmitri LaJolla, US 9 71

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