Methods of using dyes in association with nucleic acid staining or detection and associated technology

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United States of America Patent

PATENT NO 9102835
APP PUB NO 20140073058A1
SERIAL NO

13962668

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Abstract

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Methods of using dyes and associated technology are provided. A dye, such as a monomeric dye or a dimeric dye, may be used in a nucleic acid gel staining application and/or a nucleic acid detection application. Such a dye and a salt that comprises an anion that is associated with a strong acid and a cation that is associated with a strong base may be used in such an application. A dimeric dye, such as a dimeric dye capable of forming a hairpin-like structure, may be used to stain and/or detect nucleic acids via a release-on-demand mechanism. A dimeric dye having low background fluorescence in the absence of nucleic acids and high fluorescence in the presence of nucleic acids, upon binding therewith, may be used to stain and/or detect nucleic acids.

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Patent Owner(s)

  • BIOTIUM, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Leung, Wai-Yee San Ramon, US 71 1867
Mao, Fei Fremont, US 173 16239

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