Field effect transistor-based bio-sensor
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United States of America Patent
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Aug 18, 2015
Grant Date -
May 21, 2015
app pub date -
Dec 12, 2014
filing date -
Dec 21, 2012
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Abstract
An apparatus comprises: a sensing element formed on a buried oxide layer of a substrate and providing communication between a source region and a drain region; a gate dielectric layer on the sensing element, the gate dielectric layer defining a sensing surface on the sensing element; a passive surface surrounding the sensing surface; and a compound bound to the sensing surface and not bound to the passive surface, the compound having a ligand specifically configured to preferentially bind a target molecule to be sensed. An electrolyte solution in contact with the sensing surface and the passive surface forms a top gate of the apparatus.
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