Ionization method and apparatus using electrospray, and analyzing method and apparatus
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United States of America Patent
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Aug 18, 2015
Grant Date -
Oct 4, 2012
app pub date -
Jun 7, 2012
filing date -
Dec 8, 2009
priority date (Note) -
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Abstract
It is arranged so that living tissue that has not been pretreated can be adopted as a sample of interest. A sample is introduced into at least a tip portion of a hollow insulated sample holder 11 having a small hole 11a in the tip portion. A slender metal wire 12, which has been inserted into the sample holder 11 from the rear, is projected outwardly from the sample holder 11 through the hole 11a while being brought into contact with the sample. A high voltage is applied to the slender metal wire 12 at least in a portion of a time period in which the tip of the slender metal wire 12 is being projected outwardly from the hole 11a, thereby ionizing, by electrospray, the sample adhering to the tip of the slender metal wire 12. The ions are introduced into an analyzing apparatus and are analyzed.
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