Transferrin/transferrin receptor-mediated siRNA delivery

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United States of America Patent

PATENT NO 9114152
APP PUB NO 20130177580A1
SERIAL NO

13765216

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Abstract

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The invention provides interfering RNA molecule-ligand conjugates useful as a delivery system for delivering interfering RNA molecules to a cell in vitro or in vivo. The conjugates comprise a ligand that can bind to a transferrin receptor (TfR). Therapeutic uses for the conjugates are also provided.

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Patent Owner(s)

  • ARROWHEAD RESEARCH CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chatterton, Jon E Fort Worth, US 111 435
Clark, Abbot F Arlington, US 126 1311

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