Nucleic acid expression construct and its use as a cell proliferation marker

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United States of America Patent

PATENT NO 9115206
APP PUB NO 20120117668A1
SERIAL NO

13383580

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Abstract

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A nucleic acid expression construct which encodes a fusion protein includes a reporter protein and a protein with a wild-type destruction signal. A sequence encoding the fusion protein is operably linked to a non-endogenous promoter. The fusion protein localizes during a cell cycle progression to subcellular structures selected from a cell cortex, a contractile ring, and a midbody.

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Patent Owner(s)

Patent OwnerAddress
RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAET BONNREGINA-PACIS-WEG 3 BONN 53113

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fleischmann, Bernd K Bonn, DE 1 1
Hesse, Michael Bonn, DE 132 2248
Raulf, Alexandra Bonn, DE 1 1

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