Fentanyl derivatives as pH-dependent opioid receptor agonists

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United States of America Patent

PATENT NO 9133120
APP PUB NO 20140228406A1
SERIAL NO

14239461

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Abstract

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The invention relates to fluorinated fentanyl derivatives that function as opioid receptor agonists, which activate target opioid receptors in a pH-dependent manner, and are thus selective for the receptors in inflamed (acidic) milieu; uses thereof and pharmaceutical compositions comprising them.

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Patent Owner(s)

  • CHARITE-UNIVERSITATSMEDIZIN BERLIN;KONRAD-ZUSE-INSTITUT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Scharkoi, Olga Berlin, DE 1 0
Stein, Christoph Berlin, DE 9 95
Weber, Marcus Berlin, DE 31 282
Zöllner, Christian Hamburg, DE 1 0

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