FXR (NR1H4) binding and activity modulating compounds

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United States of America Patent

PATENT NO 9139539
APP PUB NO 20140221659A1
SERIAL NO

14232118

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Abstract

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The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

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Patent Owner(s)

  • GILEAD SCIENCES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kinzel, Olaf Heidelberg, DE 35 345
Kremoser, Claus Heidelberg, DE 21 491
Steeneck, Christoph Dossenheim, DE 36 297

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