Itraconazole compositions with improved bioavailability

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United States of America Patent

PATENT NO 9149431
APP PUB NO 20140005204A1
SERIAL NO

13923459

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Abstract

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A solid dispersion product comprising itraconazole and hydroxypropyl methylcellulose, which satisfies the Formula 0.35>ΔHtr (1) (wherein ΔHtr represents the endotherm (J/g) accompanying a transition at about 240° C.). The solid dispersion product shows an improved bioavailability.

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Patent Owner(s)

Patent OwnerAddress
ABBVIE DEUTSCHLAND GMBH & CO KGMAINZER STRASSE 81 WEISBADEN 65189

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berndl, Gunther Herxheim am Berg, DE 41 448
Degenhardt, Matthias Limburgerhof, DE 18 147
Dispersyn, Gerrit Princeton, US 3 45
Mägerlein, Markus Mannheim, DE 5 1

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