Process for the preparation of diol sulfones

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United States of America Patent

PATENT NO 9150562
APP PUB NO 20130303779A1
SERIAL NO

13980154

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Abstract

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The present invention relates to a process for the preparation of a diol sulfone derivative comprising reaction of a halomethyl substrate with a thio-aryl compound to obtain a thio-ether compound, and oxidizing the thio-ether compound to the corresponding sulfone. In case of a chiral halomethyl substrate, the resulting chiral diol sulfone derivative is suitable as a building block for statin type compounds.

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Patent Owner(s)

Patent OwnerAddress
DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B V2613 AX DELFT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Lange Ben Echt, NL 28 8
Heemskerk, Dennis Echt, NL 14 6
Mink, Daniel Echt, NL 17 130
Riebel, Peter Hans Echt, NL 7 0
Wolberg, Michael Echt, NL 11 218

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