Agents and methods based on the use of the EDA domain of fibronectin

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United States of America Patent

PATENT NO 9155783
SERIAL NO

11922148

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Abstract

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This invention relates to the use of a polypeptide in the production of an immunostimulatory agent, said polypeptide comprising a sequence corresponding to the EDA domain of fibronectin, a fragment of the EDA domain which can bind to TLR4 or a variant of said EDA domain or a fragment which can bind to TLR4 and which has a homology of more than 70% with any form or natural fragment of the EDA domain. The invention also relates to the production methods and applications of said agent.

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Patent Owner(s)

Patent OwnerAddress
PROYECTO DE BIOMEDICINA CIMA S LNAVARRA SPAIN NAVARRA NAVARRE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gorraiz, Ayala Marta Navarra, ES 2 6
Lasarte, Sagastibelza Juan Jose Navarra, ES 10 52
Leclerc, Claude Navarra, ES 44 363
Prieto, Valtuena Jesus Navarra, ES 13 59

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