Cartilaginous and osteochondral substitute comprising multilayer structure and use thereof
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United States of America Patent
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Oct 13, 2015
Grant Date -
Sep 17, 2009
app pub date -
Mar 2, 2006
filing date -
Mar 4, 2005
priority date (Note) -
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Abstract
The present invention relates to a multilayer structure (1) including a first upper layer (2) consisting of an organic matrix including collagen and at least a lower layer (3, 4, . . . 10) consisting of a composite matrix including hydroxylapatite and collagen. Furthermore, the present invention relates to a cartilaginous substitute including said multilayer structure (1) as well as an osteochondral substitute including said multilayer structure (1). Finally, the present invention relates to the use of said multilayer structure (1) for the preparation of said cartilaginous substitute and said osteochondral substitute for the treatment of cartilaginous defects and osteochondral defects or for the neo-formation of a cartilaginous tissue and/or a subchondral bone tissue.
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