CH2 domain template molecules derived from rational grafting of donor loops onto CH2 scaffolds

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United States of America Patent

PATENT NO 9156917
APP PUB NO 20120230981A1
SERIAL NO

13370831

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Abstract

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Novel CH2 domain template molecules wherein donor loops from a database of domains are transferred to a CH2 domain scaffold. At least one or up to three loops from a donor are transferred to the CH2 domain. The donor loops may be chosen based on length, e.g., the donor loop may have a length that is similar to that of a structural loop in the CH2 domain scaffold.

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Patent Owner(s)

  • RESEARCH CORPORATION TECHNOLOGIES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bramhill, David Tucson, US 6 17
Raghunathan, Gopalan San Diego, US 32 325

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